課程資訊
課程名稱
專題討論
Seminar 
開課學期
102-1 
授課對象
生化科技研究所  
授課教師
楊啟伸 
課號
BST7000 
課程識別碼
B22 M0020 
班次
04 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一7,8(14:20~16:20) 
上課地點
農化一第六 
備註
必修4學期。與許瑞祥、黃慶璨、張麗冠、陳進庭、林晉玄合開
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1021micro_dis_2 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
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課程概述

專題討論 

課程目標
獨立閱讀科學期刊文章能力 
課程要求
一週前大綱
30分鐘 presentation and discussion 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
 
參考書目
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
9/09  課程資訊、大綱寫作、注意事項(How to read a paper) 
第2週
9/16  Endnote 文獻管理之觀念和應用 
第3週
9/23  【林玉儒】 (Open speech for doctoral dissertation): Establishment of poly-heterologous gene expression system in Flammunila velutipes and its application on enterovirus 71 virus-like particles production 
第4週
9/30  【林明靜】(Open speech for doctoral dissertation):Study on the anti-bacterial, anti-inflammatory, and anti-cancer activities of shrimp anti-lipopolysaccharide factor (SALF), epinecidin, and pardaxin
 
第5週
10/07  【黃翔弘】(博士班):Emerging regulation and functions of autophagy <br />
Nat. Cell Biol. 15:pp713–720 (2013). <Br />

【陳昱伶】(博士班): Unraveling the complexity of hepatitis B virus: From molecular understanding to therapeutic strategy in 50 years. <BR /> The International Journal of Biochemistry & Cell Biology 45:pp1987-1996 (2013) <br /> 
第6週
10/14  【黃睦晴】(博士班):Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. <br />
Cancer Metastasis Rev. 31:pp195-208 (2012). <Br />
【梁慎桓】: White-opaque switching in natural MTLa/α isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex. <Br />
PLoS Biology 11:e1001525 (2013) 
第7週
10/21  【賴亭薇】: Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. <Br /> EMBO J 2013:pp1-13 (2013)<Br />
【蔡沛賜】:An Sp1/Sp3 site in the downstream region of varicella-zoster virus (VZV) oriS influences origin-dependent DNA replication and flanking gene transcription and is important for VZV replication in vitro and in human skin. <Br />
Journal of Virology 86: pp13070–13080 (2012) 
第8週
10/28  【李昕南】:Dopamine neurons modulate pheromone responses in Drosophila courtship learning. <br /> Nature 489:pp145-150 (2012) <Br />
【謝宛伶】:Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model. <Br />
Int. J. Cancer 131:E10–E20 (2012). 
第9週
11/04  【管彥民】:Bacteria activate sensory neurons that modulate pain and inflammation <br /> Nature 501:pp52-60 (2013). <Br />
【黃筱茜】:Interaction of herpes simplex virus ICP0 with ND10 bodies. <Br />
Journal of Virology 87:pp10244–10254 (2013) 
第10週
11/11  【黃庭儀】:AAV-Directed Persistent Expression of a Gene Encoding Anti-Nicotine Antibody for Smoking Cessation. <Br />
Sci Transl Med 27: 140ra87. doi:10.1126/ scitranslmed.3003611 (2012). <Br />
【韓怡安】:Isolation of a new Pseudomonas halophila strain possess bacteriorhodopsin-like protein by a novel method for screening of photoactive protein producing bacteria. World J. Microbial Biotechnol. DOI 10.1007/s11274-013-1453-7 (2013). 
第11週
11/18  【馮資惠】:The herpesvirus VP1/2 protein is an effector of dynein-mediated capsid transport and neuroinvasion. <Br />
Cell Host & Microbe 13:pp193–203 (2013). <Br />
【劉冠廷】:A Microbial Rhodopsin with a Unique Retinal Composition Shows Both
Sensory Rhodopsin II and Bacteriorhodopsin-like Properties <Br /> J. of Biol. Chem. 286:pp5967-5976 (2011). 
第12週
11/25  【黃彥鈞】:Efficient secretion of lipase r27RCL in Pichia pastoris. <br />
J Ind Microbiol Biotechnol. DOI 10.1007/ s10295-013-1328-9 (2013). <Br />
【蔡存傑】:Role of trimer–trimer interaction of bacteriorhodopsin studied by optical
spectroscopy and high-speed atomic force microscopy. <Br />
J. of Structual Biology 184:pp2–11 (2013).
 
第13週
12/02  【鄭仁華】:MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans. <br />
J. Biol. Chem. 286:pp42002-42016 (2011). <Br />
【張芝榕】:Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation. <Br />
PNAS 110:pp1101–1106 (2013) 
第14週
12/09  【許巧青】:Resveratrol sensitizes tamoxifen in antiestrogen-resistant breast cancer cells with epithelial-mesenchymal
transition features. <br />
Int. J. Mol. Sci. 14:pp15655-15668 (2013) <Br />
【王家瑋】:Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression. <Br />
Adv. Mater. 25:pp3532–3541 (2013). 
第15週
12/16  【林佳葳】:Agrobacterium-mediated co-transformation of rice using two selectable marker genes derived from rice genome components. <br />Plant Cell Rep: DOI 10.1007/s00299-012-1318-9 (2012) <br />
【陳筱儒】:Voltage dependence of proton pumping. <Br /> PLoS One 8:e73338 (2013). 
第16週
12/23  【張雯涵】:Identification of a Novel Response Regulator, Crr1, That Is Required for Hydrogen Peroxide Resistance in Candida albicans. <br /> PLoS One 6:e27979 (2013)<br />
【楊尉屏】:Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE&#8322;-mediated activation of β-catenin signaling. <br />
PLoS One 8:e60749 (2011)
 
第17週
12/30  【陳佩君】:Increase of salt dependence of halophilic nucleoside diphosphate kinase caused by a single amino acid substitution. <br /> Extremophiles 17:585–591 (2013)